Self-help is an important element in therapy for the handicapped.
伤残人士在治疗中，自助自立是个重要因素。
This boy is a sad case. His parents are divorced and he himself is severely handicapped.
这个男孩儿是个可怜的病儿，父母离婚，本人又严重残废。
They were handicapped by (a) poverty of resources.
他们因资源短缺处境窘迫。
